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The human microbiome-derived antimicrobial lugdunin self-regulates its biosynthesis by a feed-forward mechanism

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ABSTRACT Many human microbiome members inhibit bacterial competitors by production of antimicrobial compounds whose expression needs to be tightly controlled to balance the costs and benefits of compound biosynthesis. The nasal commensal Staphylococcus lugdunensis outcompetes Staphylococcus aureus using the antimicrobial lugdunin. The lugdunin biosynthetic gene cluster (BGC) encodes t... https://balboasurfandsstylers.shop/product-category/womens-sandal-2/
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